Obsidian Entertainment dropped the announce trailer for Side Effects Guaranteed (2026), the first chapter of a two-part paid expansion for The Outer Worlds 2. It marks the game's first substantial post-launch story content and sets up a narrative thread that continues into Spring 2027.
Official trailerPublished November 10, 2026 on the Xbox YouTube channel, the trailer is for a DLC launching December 2 on PlayStation 5, Xbox Series X|S, and PC. Developer Obsidian Entertainment and publisher Xbox Game Studios bring players to Elysium Valley, a new region on Eden, after the crew of the Incognito answers a distress call from a ship whose survivors are in cryo-stasis, infected with a contagion causing explosive cell death. Two rival Sub Rosa agents offer conflicting paths to a cure. The expansion raises the level cap to 36, adds 15-plus perks, four new flaws, new weapons, and companion outfits. Priced at $14.99 standalone, it is included with the Premium Edition. Decisions carry into the second expansion in Spring 2027.
